Princeton Medical Review: Continuous Vital-Sign Monitoring: Preventing Opioid-Induced Respiratory Depression

September, 2025 article by Anthony Rice, Princeton Medical Review

RTM Vital Signs Receives FDA Clearance for its Respiratory Monitoring System (RMS)

Philadelphia, PA — July 22, 2025 — RTM Vital Signs, LLC, a leader in advanced respiratory monitoring, proudly announces that its 1st generation Respiratory Monitoring System (RMS GEN I) has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) as a wearable device that continuously measures a patient’s respiratory rate. The RMS GEN […]

SASM: Safety of Patients with Obstructive Sleep Apnea in the Perioperative Period

By: Mandeep Singh, MBBS, MD, MSc, FRCPC; Jennifer E. Dominguez, MD, MHS; Melanie Lyons, PhD, ACNP; Satya Krishna Ramachandran, MD, MBA; Bhargavi Gali, MD, MHA SUMMARY: SASM Creating Guidelines of Postoperative Management For OSA Patients Obstructive sleep apnea (OSA), a prevalent sleep-related breathing disorder in perioperative environments, is characterized by repeated upper airway collapses that […]

Opioid-Induced Respiratory Depression—Pediatric Considerations

By: Tricia Vecchione, MD, MPH; Constance L. Monitto, MD SUMMARY: Opioid-induced respiratory depression can be a life-threatening, albeit preventable, complication in children. It is imperative to identify those at risk for opioid-induced respiratory depression and formulate safer practices, including the use of opioid-sparing adjuncts, frequent sedation assessment and vigilant monitoring. Unfortunately, no models designed to […]

Minute Ventilation as a Measure of Fitness and Endurance

By: RTM Vital Signs LLC When exercising, a person will breathe deeper and more often in order to supply the muscles with the oxygen (energy) they need and to remove carbon dioxide (waste). Exercise, over time, will increase the strength and function of muscles, making them more efficient – requiring a lower amount of oxygen […]

Continuous Clinical Surveillance: A real-time solution for comprehensive patient safety

Key advancements in real-time healthcare and advanced data analysis present a significant opportunity for health systems to push patient safety initiatives into the realm of proactive healthcare. A new Bernoulli Health white paper, Continuous Clinical Surveillance: A Real-Time Solution for Comprehensive Patient Safety leverages peer-reviewed research, literature reviews, market analysis and use-cases to demonstrate how broader […]

High-Definition Medicine

By: Ali Torkamani, Kristian G. Andersen, Steven R. Steinhubl, and Eric J. Topol, MD Abstract: The foundation for a new era of data-driven medicine has been set by recent technological advances that enable the assessment and management of human health at an unprecedented level of resolution—what we refer to as high-definition medicine. Our ability […]

Digital Medicine: Virtual Care for Improved Global Health

By: Steven R Steinhubl, Kwang-il Kim, Toluwalase Ajayi, Eric J Topol Abstract: The ability to provide health care almost anywhere in the world, inconceivable just years ago, is now possible. With time, the connectivity infrastructure will become more robust, and digital technologies will multiply in variety as they also continue to decrease in size […]

Moving From Digitalization to Digitization in Cardiovascular Care

By: Steven R. Steinhubl, MD, Eric J. Topol, MD Abstract: So far, the digitization of health care is best exemplified by electronic medical records, which have been far from favorably or uniformly accepted. However, properly implemented digitization can enable better patient outcomes, improve convenience, potentially lower healthcare costs, and possibly lead to much greater […]

Limitations of the usual blood-pressure hypothesis and importance of variability, instability, and episodic hypertension

By: Peter M Rothwell Abstract: Although hypertension is the most prevalent treatable vascular risk factor, how it causes end-organ damage and vascular events are poorly understood. Yet, a widespread belief exists that underlying usual blood pressure can alone account for all blood-pressure-related risk of vascular events and for the benefits of antihypertensive drugs, and […]

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